The market for weight-loss treatments is expected to see 16 new drugs vying for a slice of the lucrative business currently dominated by Novo Nordisk and Eli Lilly, according to estimates from analysts at Morningstar and Pitchbook.

In a joint report published Monday, analysts estimated the market for obesity treatments could expand to $200 billion by 2031. The 16 drugs could launch by 2029, with roughly $70 billion of the GLP-1 market coming from these new challengers.

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WHY IT'S IMPORTANT

Surging demand for Novo's Wegovy and Lilly's Zepbound has sparked interest among competitors to test their own weight-loss treatments. Companies such as Amgen and Pfizer are currently testing their drug candidates in clinical trials.

These developments come amid criticism from lawmakers over the high costs associated with these medications. The new entrants, however, are expected to drive down prices as they vie for market share, according to the report.

CONTEXT

The potential new treatments include those from Boehringer Ingelheim and Zealand Pharma, along with competitors from Roche, Amgen and Pfizer, according to the report, provided that the drugs clear clinical trials.

Other entrants include those by Structure Therapeutics , Viking Therapeutics and Altimmune, along with next-generation drugs by Novo and Lilly.

Analysts, last year, had forecast the obesity market would be $170 billion by 2031, but have recently raised their estimates, partly due to anticipated higher diabetes market penetration.

The report projects 41% individuals with diabetes and nearly one-quarter of nondiabetic obesity patients will be on a GLP-1 drug by 2031.

WHAT'S NEXT

Analysts expect significant acquisitions by major pharmaceutical companies in the obesity sector over the next 18 months, targeting smaller companies specializing in obesity drug development.

Potential acquisition targets include firms such as Structure, Viking and Altimmune.

Private companies such as NodThera, Corteria and Diasome have a higher-than-50% chance of being acquired, according to PitchBook data.