Greenland is not for sale, its prime minister said Monday, responding to comments made by President-elect Donald Trump regarding the "ownership and control" of the vast Arctic island that has been part of Denmark for over 600 years.

"Greenland is ours. We are not for sale and will never be for sale. We must not lose our long struggle for freedom," the island's prime minister, Mute Egede, said in a written comment.

Trump on Sunday announced that he picked Ken Howery, a former envoy to Sweden, as his ambassador to Copenhagen, and commented on the status of Greenland, a semiautonomous part of Denmark and host to a large U.S. Air Force base.

"For purposes of National Security and Freedom throughout the World, the United States of America feels that the ownership and control of Greenland is an absolute necessity," Trump wrote on Truth Social.

Trump, who takes office on Jan. 20, did not elaborate on the statement.

Denmark's foreign ministry and the prime minister's office were not immediately available for comment.

The Danish government must state in clear terms that control over Greenland is not up for discussion or negotiation, Rasmus Jarlov, a member of Parliament from the opposition Conservative Party, posted on X.

"To the extent that U.S. activities aim to take control of Danish territory, it must be prohibited and countered. Then they can't be there at all," said Jarlov, who heads Parliament's defense committee.

The island, whose capital Nuuk is closer to New York than the Danish capital Copenhagen, boasts mineral, oil, and natural gas wealth. But development has been slow, leaving its economy reliant on fishing and annual subsidies from Denmark.

With its Pituffik Space Base, Greenland is strategically important for the U.S. military and its ballistic missile early-warning system, since the shortest route from Europe to North America runs via the island.

During his previous term in office, Trump in 2019 expressed interest in buying Greenland, but the proposal was promptly rejected by Denmark as well as by the island's own authorities before any formal discussions could take place.

Danish Prime Minister Mette Frederiksen at the time labeled Trump's offer "absurd," leading him to term her dismissal of the idea as "nasty" and to subsequently cancel a visit to Copenhagen.

Since 2009, Greenland has held the right to declare independence from Denmark. The island of some 56,000 inhabitants, which relies on significant budget transfers from Copenhagen each year, has refrained from doing so.

Separately on Sunday, Trump threatened to reassert U.S. control over the Panama Canal, accusing that country of charging excessive rates to use the Central American passage and drawing a sharp rebuke from Panamanian President Jose Raul Mulino.