The Middle East moved closer to a long-feared regional war Wednesday, a day after Iran fired a barrage of missiles at Israel and Israel said it began limited ground incursions into Lebanon targeting the Iran-backed Hezbollah militia.

Israel said it intercepted many of the missiles, and officials in Washington said U.S. destroyers assisted in Israel's defense. Iran said most of its missiles hit their targets. There have been no reports of casualties.

Israeli Prime Minister Benjamin Netanyahu vowed late Tuesday to retaliate against Iran, which he said “made a big mistake tonight and it will pay for it.” An Iranian commander threatened wider strikes on infrastructure if Israel retaliates. U.S. President Biden said Wednesday that he would not support an Israeli attack targeting Iran's nuclear program.

The United Nations Security Council held an emergency meeting for Wednesday to address the spiraling conflict.

Israel said Wednesday that eight of its soldiers have been killed in combat in southern Lebanon.

Israel and Hezbollah have traded fire across the Lebanon border almost daily since the day after Hamas’ cross-border attack on Oct. 7, 2023, which killed 1,200 Israelis and took 250 others hostage. Israel declared war on the militant group in the Gaza Strip in response. More than 41,000 Palestinians have been killed in the territory, and just over half the dead have been women and children, according to local health officials.

Direct hit

At least one aircraft hangar at a key Israeli military air base appears to have taken a direct hit during a massive barrage of Iranian missiles, according to a satellite image analyzed by The Associated Press.

Images of the Nevatim air base in southern Israel on Wednesday show a large hole blown in the roof of a row of buildings near the main runway. Large pieces of debris can be seen spread around the building.

Israel’s military did not immediately respond to a request for comment about the satellite images.

Nevatim is home to the Israeli Air Force’s most advanced aircraft, including U.S.-produced F-35 Lightening II stealth fighter jets. It is not clear from the satellite imagery whether any aircraft were in the hanger when it was struck.

Nevatim also sustained light damage during an Iranian missile and drone attack in April.

Lebanon weighs in

Lebanon’s U.N. ambassador says his government rejects the war between Israel and Hezbollah militants in the country.

Hadi Hachem told an emergency meeting of the U.N. Security Council Wednesday that the government wants the enforcement of a U.N. Security Council resolution that was supposed to end the last Israel-Hezbollah war in 2006. It called for all armed groups, including Hezbollah, to be disarmed and the deployment of Lebanese forces to the southern border with Israel. None of this has happened.

The Lebanese ambassador said fully implementing the resolution is the only solution to the ongoing war and Israel’s “barbaric aggression.” He said Lebanon is opening enlistment for 1,500 new soldiers to strengthen the national army’s presence in the south.

“Lebanon today is stuck between the Israeli destruction machine and the ambitions of others in the region,” Hachem said, alluding to Iran’s support for Hezbollah.

Americans flee

The State Department says about 100 American citizens and family members have left Lebanon on a flight contracted with a commercial airline.

Department spokesman Matthew Miller said Wednesday that the flight to Istanbul was not a charter flight but also was not on the Lebanese national carrier Middle East Airlines, which is the only commercial airline flying scheduled flights in and out of Beirut.

Since Sept. 28, MEA has made about 800 seats on its flights out of Beirut available for American citizens, but Miller could not say how many had taken those MEA flights.

He said some 6,000 American citizens have now asked for information from the U.S. Embassy in Beirut on how they might be able to leave the country, although only a small fraction of those have asked for actual assistance.

Escape to Syria

Thousands of Syrians and Lebanese continue to pour into Syria to escape Israeli airstrikes in southern Lebanon.

On Wednesday, an Associated Press team saw hundreds crowding the Jousieh border crossing, one of several points of entry into Syria. The crossing is around 30 kilometers (18 miles) from Syria’s central city of Homs, where many said they were headed.

Most of those waiting to enter Syria were from eastern Lebanon’s city of Baalbek and surrounding areas, which have been hard hit by Israeli airstrikes in recent days. The militant group Hezbollah has a strong presence in that region, but many of those killed and wounded have been civilians.

Some came from as far as the southern suburbs of Beirut.

Ola Hallaq, her husband and two kids were among those waiting to be processed. Originally from Homs, she fled Syria at the start of the civil war in 2011 and settled in Baalbek. Now, as Israel pounds eastern Lebanon, the family is returning home despite the uncertainty and lack of income.

“I’m returning to my country because of the war … there was so much destruction all around,” she said.

Dabbah Mashaal, an official at the crossing, said 10,000 displaced Syrians and 7,700 Lebanese have crossed the border in recent days.

UN Ire

The United Nations says Israel’s ban on Secretary-General Antonio Guterres entering the country is a “political statement.”

U.N. spokesperson Stephane Dujarric told reporters Wednesday that Foreign Minister Israel Katz saying Guterres is “persona non grata” is “one more attack on the United Nations staff that we’ve seen from the government of Israel.”

Katz accuses Guterres of being biased against Israel, and says he never condemned Hamas’ Oct. 7 attacks on southern Israel. Israel also claims staff from the U.N. aid agency helping Palestinian refugees, UNRWA, are Hamas members who participated in the Oct. 7 attacks.

Dujarric countered that Guterres has repeatedly condemned the Hamas attacks and sexual violence, and stressed that the U.N. still engages with Israel “at the operational level and other levels.”

JOINT BASE ANDREWS, Md. — President Joe Biden says he will not support an Israeli attack on sites related to Tehran’s nuclear program.

“The answer is no,” Biden said Wednesday, when asked if he would support such retaliation after Iran fired about 180 missiles at Israel on Tuesday.

Biden’s comments came after he and fellow Group of Seven leaders spoke by phone on Wednesday to discuss coordinating new sanctions against Iran.

The White House said in a statement that the G7 leaders “unequivocally condemned Iran’s attack against Israel” and Biden reiterated the United States’ “full solidarity and support to Israel and its people.”

All the while, the administration has signaled that it’s urging that Israel display restraint in how it responds to Tuesday’s missile attack, which Biden said was “ineffective and defeated.”

Hamas claims responsibility

Hamas’ military wing has claimed responsibility for a mass shooting in Tel Aviv that left seven people dead and wounded 16 more.

It said the two attackers, Mohammed Mesek and Ahmed Himouni, were its militants who hailed from the southern West Bank city of Hebron.

Israeli police said the two opened fire Tuesday evening in the Jaffa neighborhood of Tel Aviv, including shooting directly into a light rail carriage crowded with passengers that was stopped at a station. Police said the pair were shot and killed by security guards and armed pedestrians.

The attack came moments before Iran launched a massive barrage of rockets towards Israel, sending people into bomb shelters across the country.

It remains unclear how the two men entered Israel from the West Bank. Hamas, which has ruled Gaza since 2007, is active in various cities and refugee camps in the West Bank.

On Wednesday, locals left flowers and candles at the train stop, where bullet holes peppered the signs and benches.

Maya Brandwine said she was at a coffee shop on the street when the shooting broke out. During the subsequent Iranian missile attack, she took cover in a bomb shelter as police swept for suspects.

“It’s a nightmare, and we’re starting to get used to it,” she said, blaming the policies of Prime Minister Benjamin Netanyahu and far-right National Security Minister Itamar Ben-Gvir for the violence.