Drs. Mehmet Oz and Dr. Mike Roizen
Dr. Mehmet Oz is host of the popular TV show “The Dr. Oz Show.” He is a professor in the Department of Surgery at Columbia University and directs the Cardiovascular Institute and Complementary Medicine Program and New York-Presbyterian Hospital.

Dr. Mike Roizen is chief medical officer at the Cleveland Clinic Wellness Institute, an award-winning author, and has been the doctor to eight Nobel Prize winners and more than 100 Fortune 500 CEOs.

Dr. Mehmet Oz,Dr. Mike Roizen

Tags: perimenopause | hormone therapy | dementia | dr. roizen
OPINION

Dealing With Perimenopause

Michael Roizen, M.D. By Wednesday, 14 May 2025 04:39 PM EDT Current | Bio | Archive

Perimenopause is the time when hormone fluctuations (and the associated symptoms) mean you're heading to the complete cessation of your periods, called menopause. It often starts in your mid-40s and lasts eight to 10 years.

But how each person experiences it can vary as wildly as the symptoms.

Contending with those symptoms — which may include hot flashes, brain fog, night sweats, low libido, insomnia, urination urgency, and vaginal dryness — can be challenging. And according to new research, this leads to even greater health challenges down the road.

A study in the journal PLOS One identified a connection between the amount of perimenopause symptoms you have and an increased risk of cognition problems, behavioral changes, and dementia later in life.

Fortunately, the researchers also found a helpful remedy: estrogen-based hormone therapy, which significantly reduced study participants' risk of later-in-life behavioral problems such as lack of motivation, impulsiveness, and difficulty with social interaction.

If you're experiencing difficult perimenopause symptoms, the Cleveland Clinic suggests doing weight-bearing exercises; eating plenty of fruits, vegetables, whole grains, lean proteins, and healthy fats; adopting stress-reducing techniques such as meditation; and limiting alcohol and caffeine intake.

In addition to hormone therapy (used with low-dose aspirin and plenty of water to avoid a blood clot, if your doctor agrees), medical solutions include taking gabapentin, fezolinetant, oxybutynin, and antidepressants to ease hot flashes. 

For more ways to stay brain-healthy, check out my book "The Great Age Reboot."

© King Features Syndicate


Dr-Oz
Research identified a connection between the amount of perimenopause symptoms you have and an increased risk of cognition problems, behavioral changes, and dementia later in life.
perimenopause, hormone therapy, dementia, dr. roizen
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2025-39-14
Wednesday, 14 May 2025 04:39 PM
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